Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: Results from a prospective, randomized sham‐controlled trial
Identifieur interne : 002715 ( Main/Exploration ); précédent : 002714; suivant : 002716Pallidal deep brain stimulation improves quality of life in segmental and generalized dystonia: Results from a prospective, randomized sham‐controlled trial
Auteurs : Joerg Mueller [Allemagne] ; Inger M. Skogseid [Allemagne] ; Reiner Benecke [Allemagne] ; Andreas Kupsch [Allemagne] ; Thomas Trottenberg [Allemagne] ; Werner Poewe [Allemagne] ; Gerd H. Schneider [Allemagne] ; Wilhelm Eisner [Allemagne] ; Alexander Wolters [Allemagne] ; J. U. Müller [Allemagne] ; Günther Deuschl [Allemagne] ; Marcus O. Pinsker [Allemagne] ; Geir K. Roeste [Allemagne] ; Juliane Vollmer-Haase [Allemagne] ; Angela Brentrup [Allemagne] ; Martin Krause [Allemagne] ; Volker Tronnier [Allemagne] ; Alfons Schnitzler [Allemagne] ; Jüergen Voges [Allemagne] ; Guido Nikkhah [Allemagne] ; Jan Vesper [Allemagne] ; Markus Naumann [Allemagne] ; Jens Volkmann [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Prospective.
English descriptors
- KwdEn :
- Adult, Deep Brain Stimulation (methods), Deep brain stimulation, Depressive Disorder (diagnosis), Depressive Disorder (psychology), Disability Evaluation, Double-Blind Method, Dystonia, Dystonia (diagnosis), Dystonia (physiopathology), Dystonia (therapy), Female, Globus Pallidus (physiopathology), Humans, Male, Nervous system diseases, Placebos, Prospective, Prospective Studies, Quality of Life (psychology), Quality of life, Questionnaires, Severity of Illness Index, deep brain stimulation, dystonia, globus pallidus internus, quality of life.
- MESH :
- chemical : Placebos.
- diagnosis : Depressive Disorder, Dystonia.
- methods : Deep Brain Stimulation.
- physiopathology : Dystonia, Globus Pallidus.
- psychology : Depressive Disorder, Quality of Life.
- therapy : Dystonia.
- Adult, Disability Evaluation, Double-Blind Method, Female, Humans, Male, Prospective Studies, Questionnaires, Severity of Illness Index.
Abstract
As part of the first randomized, sham‐timulation controlled trial on deep brain stimulation (DBS) in primary segmental or generalized dystonia, health‐related quality of life (HRQoL) was assessed by SF‐36. After the 3‐month sham‐controlled phase, significant HRQoL improvement occurred only in the active‐stimulation group. The open‐label extension phase resulted in a significant improvement in all SF‐36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21783
Affiliations:
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Deep Brain Stimulation (methods)</term>
<term>Deep brain stimulation</term>
<term>Depressive Disorder (diagnosis)</term>
<term>Depressive Disorder (psychology)</term>
<term>Disability Evaluation</term>
<term>Double-Blind Method</term>
<term>Dystonia</term>
<term>Dystonia (diagnosis)</term>
<term>Dystonia (physiopathology)</term>
<term>Dystonia (therapy)</term>
<term>Female</term>
<term>Globus Pallidus (physiopathology)</term>
<term>Humans</term>
<term>Male</term>
<term>Nervous system diseases</term>
<term>Placebos</term>
<term>Prospective</term>
<term>Prospective Studies</term>
<term>Quality of Life (psychology)</term>
<term>Quality of life</term>
<term>Questionnaires</term>
<term>Severity of Illness Index</term>
<term>deep brain stimulation</term>
<term>dystonia</term>
<term>globus pallidus internus</term>
<term>quality of life</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Placebos</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Depressive Disorder</term>
<term>Dystonia</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dystonia</term>
<term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Depressive Disorder</term>
<term>Quality of Life</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dystonia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Disability Evaluation</term>
<term>Double-Blind Method</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Prospective Studies</term>
<term>Questionnaires</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Dystonie</term>
<term>Pathologie du système nerveux</term>
<term>Prospective</term>
<term>Qualité de vie</term>
<term>Stimulation cérébrale profonde</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Prospective</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">As part of the first randomized, sham‐timulation controlled trial on deep brain stimulation (DBS) in primary segmental or generalized dystonia, health‐related quality of life (HRQoL) was assessed by SF‐36. After the 3‐month sham‐controlled phase, significant HRQoL improvement occurred only in the active‐stimulation group. The open‐label extension phase resulted in a significant improvement in all SF‐36 domains following 6 months of neurostimulation. These results demonstrate a favorable impact of DBS on HRQoL in primary dystonia. © 2007 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>Schleswig-Holstein</li>
<li>Tyrol (Land)</li>
</region>
<settlement><li>Innsbruck</li>
<li>Kiel</li>
</settlement>
<orgName><li>Université de médecine d'Innsbruck</li>
</orgName>
</list>
<tree><country name="Allemagne"><region name="Schleswig-Holstein"><name sortKey="Mueller, Joerg" sort="Mueller, Joerg" uniqKey="Mueller J" first="Joerg" last="Mueller">Joerg Mueller</name>
</region>
<name sortKey="Benecke, Reiner" sort="Benecke, Reiner" uniqKey="Benecke R" first="Reiner" last="Benecke">Reiner Benecke</name>
<name sortKey="Brentrup, Angela" sort="Brentrup, Angela" uniqKey="Brentrup A" first="Angela" last="Brentrup">Angela Brentrup</name>
<name sortKey="Deuschl, Gunther" sort="Deuschl, Gunther" uniqKey="Deuschl G" first="Günther" last="Deuschl">Günther Deuschl</name>
<name sortKey="Eisner, Wilhelm" sort="Eisner, Wilhelm" uniqKey="Eisner W" first="Wilhelm" last="Eisner">Wilhelm Eisner</name>
<name sortKey="Krause, Martin" sort="Krause, Martin" uniqKey="Krause M" first="Martin" last="Krause">Martin Krause</name>
<name sortKey="Kupsch, Andreas" sort="Kupsch, Andreas" uniqKey="Kupsch A" first="Andreas" last="Kupsch">Andreas Kupsch</name>
<name sortKey="Muller, J U" sort="Muller, J U" uniqKey="Muller J" first="J. U." last="Müller">J. U. Müller</name>
<name sortKey="Naumann, Markus" sort="Naumann, Markus" uniqKey="Naumann M" first="Markus" last="Naumann">Markus Naumann</name>
<name sortKey="Nikkhah, Guido" sort="Nikkhah, Guido" uniqKey="Nikkhah G" first="Guido" last="Nikkhah">Guido Nikkhah</name>
<name sortKey="Pinsker, Marcus O" sort="Pinsker, Marcus O" uniqKey="Pinsker M" first="Marcus O." last="Pinsker">Marcus O. Pinsker</name>
<name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name>
<name sortKey="Roeste, Geir K" sort="Roeste, Geir K" uniqKey="Roeste G" first="Geir K." last="Roeste">Geir K. Roeste</name>
<name sortKey="Schneider, Gerd H" sort="Schneider, Gerd H" uniqKey="Schneider G" first="Gerd H." last="Schneider">Gerd H. Schneider</name>
<name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<name sortKey="Skogseid, Inger M" sort="Skogseid, Inger M" uniqKey="Skogseid I" first="Inger M." last="Skogseid">Inger M. Skogseid</name>
<name sortKey="Tronnier, Volker" sort="Tronnier, Volker" uniqKey="Tronnier V" first="Volker" last="Tronnier">Volker Tronnier</name>
<name sortKey="Trottenberg, Thomas" sort="Trottenberg, Thomas" uniqKey="Trottenberg T" first="Thomas" last="Trottenberg">Thomas Trottenberg</name>
<name sortKey="Vesper, Jan" sort="Vesper, Jan" uniqKey="Vesper J" first="Jan" last="Vesper">Jan Vesper</name>
<name sortKey="Voges, Juergen" sort="Voges, Juergen" uniqKey="Voges J" first="Jüergen" last="Voges">Jüergen Voges</name>
<name sortKey="Volkmann, Jens" sort="Volkmann, Jens" uniqKey="Volkmann J" first="Jens" last="Volkmann">Jens Volkmann</name>
<name sortKey="Vollmer Aase, Juliane" sort="Vollmer Aase, Juliane" uniqKey="Vollmer Aase J" first="Juliane" last="Vollmer-Haase">Juliane Vollmer-Haase</name>
<name sortKey="Wolters, Alexander" sort="Wolters, Alexander" uniqKey="Wolters A" first="Alexander" last="Wolters">Alexander Wolters</name>
</country>
</tree>
</affiliations>
</record>
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